| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5358770 | Applied Surface Science | 2009 | 6 Pages |
Abstract
Nanostructuring waveguides by means of block-copolymer assisted lithography has as effect an increase in the total surface area. The non-specific adsorption of proteins on the nanostructured surfaces was monitored by wavelength-interrogated optical sensing and an increase in the sensitivity of the detection as compared to flat chips was observed. A model of the adsorption process confirmed the obtained experimental results and allowed the design of experimental approaches through which the detection sensitivity can be further improved.
Related Topics
Physical Sciences and Engineering
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Physical and Theoretical Chemistry
Authors
Ana Maria Popa, Bernard Wenger, Emmanuel Scolan, Guy Voirin, Harry Heinzelmann, Raphael Pugin,