Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5362930 | Applied Surface Science | 2011 | 9 Pages |
Abstract
⺠Implants consisting of indomethacin coated with polymeric films were produced by MAPLE. ⺠The implants were tested in vitro in conditions close to those encountered inside the body. ⺠The implants containing PEG:PLGA films exhibit enhanced biocompatibility. ⺠The implants containing PEG:PLGA films offer prolonged release rates of the drug. ⺠The drug release is controlled by a diffusion mediated mechanism (Higuchi's model).
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Authors
Irina Alexandra Paun, Antoniu Moldovan, Catalin Romeo Luculescu, Maria Dinescu,