| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5365136 | Applied Surface Science | 2008 | 4 Pages |
Abstract
The promising application of functionalized gold nanoparticles to amplify the performance of biosensors and relevant biomolecular recognition processes has been explored in this paper. Our observations illustrate the apparent enhancement effect of the gold nanoparticles on the electrochemical response of the anticancer drug dacarbazine (DTIC) binding to DNA and DNA bases, indicating that these functionalized gold nanoparticles could readily facilitate the specific interactions between DTIC and DNA/DNA bases. This raises the potential valuable applications of these biocompatible nanoparticles in the promising biosensors and biomedical engineering.
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Physical Sciences and Engineering
Chemistry
Physical and Theoretical Chemistry
Authors
Qin Shen, Xuemei Wang, Degang Fu,