Article ID Journal Published Year Pages File Type
5370740 Biophysical Chemistry 2016 7 Pages PDF
Abstract

•A two-component model of DNA is studied.•Dynamics of the transcription bubble.•Non-linear longitudinal compression.

The dependence of the dynamics of transcription bubble on the parameters of non-linear longitudinal compression is presented on the base of simple model of soliton-like conformational switchings in two-component bistable polymer molecules with energetically non-equivalent stable states. It has been shown that under certain conditions the longitudinal compression may be a trap for a conformational switching.

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Physical Sciences and Engineering Chemistry Physical and Theoretical Chemistry
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