| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5372054 | Biophysical Chemistry | 2007 | 9 Pages |
Abstract
The synthesis, characterization and liposome insertion of a novel magnesium(II) carboranyl-porphyrazine, i.e. [2,3,7,8,12,13,17,18-octakis-(1,2-dicarba-closo-dodecaboranyl)-hexylthio-5,10,15,20-porphyrazine]magnesium(II) complex, MgHECSPz, are described. MgHECSPz was designed to improve the potentiality in multiple approach anticancer therapy. Liposomal formulations with different surface charge were prepared as delivering agents. The obtained loaded vectors were characterized by DLS, SAXS, SANS and zeta potential measurements in order to define the overall properties and structural details of loaded liposomes.
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Chemistry
Physical and Theoretical Chemistry
Authors
Anna Salvati, Sandra Ristori, Daniela Pietrangeli, Julian Oberdisse, Luca Calamai, Giacomo Martini, Giampaolo Ricciardi,