Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5373965 | Chemical Physics | 2013 | 6 Pages |
Abstract
⺠Phospholipid flip-flop in transmembrane peptide-containing vesicles was investigated. ⺠Peptides that contained polar residues in the center of the transmembrane region promoted phospholipid flip-flop. ⺠A bioinformatics approach revealed the presence of polar residues in the transmembrane region of ER membrane proteins. ⺠Polar residues in ER membrane proteins possibly provide flippase-like activity.
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Authors
Masanori Kaihara, Hiroyuki Nakao, Hirokazu Yokoyama, Hitoshi Endo, Yasushi Ishihama, Tetsurou Handa, Minoru Nakano,