Article ID Journal Published Year Pages File Type
5379470 Chemical Physics Letters 2015 7 Pages PDF
Abstract

- Three targeting drug delivery systems were formulated by functionalization of single-walled carbon nanotubes using biopolymers for delivery of doxorubicin.
- Applying Carboxymethyl Chitosan instead chitosan for functionalization led to 10% increase in loading efficiency.
- Release rate can be adjusted by changing the hydrophobic/hydrophilic substitution degree ratios.
- Folic acid attachment led to 15% decrease in cancer cell viability.
- NPCS-SWNT shows the slowest (30%) and CS-SWNT has the highest release rate (70%) of the DOX.
Related Topics
Physical Sciences and Engineering Chemistry Physical and Theoretical Chemistry
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