Article ID Journal Published Year Pages File Type
5379617 Chemical Physics Letters 2015 7 Pages PDF
Abstract

- We examine the stability of the PCNA - a ring shape protein interacting with DNA.
- Determinants of the mechanical stability are studied by steered molecular dynamics.
- PCNA exhibits a mechanical propensity toward adapting circular shape.
- The N- and C-terminal domains are strongly coupled but have different mechanical resilience.
Related Topics
Physical Sciences and Engineering Chemistry Physical and Theoretical Chemistry
Authors
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