Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5379617 | Chemical Physics Letters | 2015 | 7 Pages |
Abstract
- We examine the stability of the PCNA - a ring shape protein interacting with DNA.
- Determinants of the mechanical stability are studied by steered molecular dynamics.
- PCNA exhibits a mechanical propensity toward adapting circular shape.
- The N- and C-terminal domains are strongly coupled but have different mechanical resilience.
Related Topics
Physical Sciences and Engineering
Chemistry
Physical and Theoretical Chemistry
Authors
Jakub Rydzewski, Wojciech Strzalka, Wieslaw Nowak,