| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5381203 | Chemical Physics Letters | 2014 | 4 Pages |
Abstract
- Lys38 and Glu55 interact with each other, with different outcomes for C40 and C39.
- Glu91 is the most significant residue for C39 binding.
- Glu55 strongly repel C39 from the Chk1 active site.
- Glu55 repel significantly C40.
- C39 is more powerful inhibitor of Chk1 than C40.
Related Topics
Physical Sciences and Engineering
Chemistry
Physical and Theoretical Chemistry
Authors
Pedro M.M. Araújo, LuÃs Pinto da Silva, Joaquim C.G. Esteves da Silva,