| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5382187 | Chemical Physics Letters | 2013 | 6 Pages |
Abstract
⺠Acidities of peptide backbone NH protons have been analyzed through quantum chemical calculations. ⺠Predicted acidities exhibit a strong dependence on backbone conformation in both gas phase and aqueous solution. ⺠The first hydration shell plays a key role. ⺠In water, the most acidic NH protons should be those involved in some β-turns.
Related Topics
Physical Sciences and Engineering
Chemistry
Physical and Theoretical Chemistry
Authors
Antoni Oliva, Bernard Henry, Manuel F. Ruiz-López,