Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5382674 | Chemical Physics Letters | 2013 | 26 Pages |
Abstract
⺠P-glycoprotein (P-gp) is a multidrug transporter. ⺠Molecular dynamics simulations using the X-ray crystal structure of mouse P-gp. ⺠Dimerization of the nucleotide binding domains (NBDs). ⺠Allosteric communication between the NBDs and the transmembrane domains. ⺠Role of ATP and substrate.
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Authors
Yurika Watanabe, Wei-Lin Hsu, Shuntaro Chiba, Tomohiko Hayashi, Tadaomi Furuta, Minoru Sakurai,