Article ID Journal Published Year Pages File Type
5382674 Chemical Physics Letters 2013 26 Pages PDF
Abstract
► P-glycoprotein (P-gp) is a multidrug transporter. ► Molecular dynamics simulations using the X-ray crystal structure of mouse P-gp. ► Dimerization of the nucleotide binding domains (NBDs). ► Allosteric communication between the NBDs and the transmembrane domains. ► Role of ATP and substrate.
Related Topics
Physical Sciences and Engineering Chemistry Physical and Theoretical Chemistry
Authors
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