| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5383571 | Chemical Physics Letters | 2012 | 9 Pages |
Abstract
⺠Multiprotein complex ions unfold via sequential pathways in the gas phase. ⺠Multiprotein complexes primarily unfold via conformational changes in a single monomeric unit. ⺠The addition of involatile buffer salts prior to electrospray ionisation preferentially stabilizes the 'native-like' gas-phase conformers of protein complex ions. ⺠Adducts do not influence the global structure of protein complexes, only the energetics of their formation.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Physical and Theoretical Chemistry
Authors
Joanna Freeke, Matthew F. Bush, Carol V. Robinson, Brandon T. Ruotolo,