Article ID Journal Published Year Pages File Type
5384684 Chemical Physics Letters 2011 5 Pages PDF
Abstract
► Four different adducts of AMD473 with a duplex DNA are possible. ► Proton transfer between DNA base pairs of the stable drug-DNA adducts are possible. ► Energy difference of single proton transferred and original structure is very small. ► Base pair modification via proton transfer may be the cause of DNA damage.
Related Topics
Physical Sciences and Engineering Chemistry Physical and Theoretical Chemistry
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