| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5385098 | Chemical Physics Letters | 2010 | 4 Pages |
Abstract
⺠HuPrP(109-111) covers the copper-binding site around His111 in HuPrP(106-126). ⺠Redox activities of Cu-HuPrP(109-111) complexes depend on copper-binding conformations. ⺠Nâ-rich coordinations show high Cu(II)/Cu(III) oxidation activities. ⺠Methionine-interacted models have high Cu(II)/Cu(I) reduction activities. ⺠Such diverse redox behaviors could be involved in the neurotoxic mechanism of HuPrP(106-126).
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Authors
Norifumi Yamamoto, Kazuo Kuwata,