Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5390149 | Chemical Physics Letters | 2006 | 6 Pages |
Abstract
Fluorescence quenching by dye dimer formation has been utilized to develop hairpin-structured DNA probes for the detection of a single nucleotide polymorphism (SNP) in DNA sequences implicated in the penicillin resistance of Streptococcus pneumoniae. Depending on the target DNA either the green-labeled or the red-labeled DNA probe is opened and thus fluoresces.
Related Topics
Physical Sciences and Engineering
Chemistry
Physical and Theoretical Chemistry
Authors
Nicole Marmé, Achim Friedrich, Dalia Denapaite, Regine Hakenbeck, Jens-Peter Knemeyer,