The Trp-cage miniprotein with single-site mutations: Studies of stability and dynamics using molecular dynamics

Article ID	Journal	Published Year	Pages	File Type
5394929	Computational and Theoretical Chemistry	2011	8 Pages	PDF

Abstract

âº The respective role of each Trp-cage residue was studied for its stability and dynamics. âº Three key residues of the Trp-cage were identified. âº The Asp9/Arg16 salt-bridge was found to be intrinsic in the Trp-cage and not readily affected.

Keywords

H-bonds Hydrophobic interactions mutation Molecular dynamics

Related Topics

Physical Sciences and Engineering Chemistry Physical and Theoretical Chemistry

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The Trp-cage miniprotein with single-site mutations: Studies of stability and dynamics using molecular dynamics

Authors

Xiaomin Wu, Gang Yang, Yuangang Zu, Yujie Fu, Lijun Zhou, Xiaohui Yuan,