A new thin film optical sensor for assessment of UO22+ based on the fluorescence quenching of Trimetazidine doped in sol gel matrix

A new, simple and sensitive method for the assessment of UO22+ was developed. The method is based on the quenching of the fluorescence intensity of the thin film optical sensor 1-(2,3,4-trimethoxybenzyl) piperazine [Trimetazidine] doped in sol gel matrix in the presence of different UO22+ concentrations in DMSO. The remarkable quenching of the fluorescence intensity of Trimetazidine by various UO22+ concentrations was successfully used as a new optical sensor for the assessment of UO22+ in DMSO at λex/λem=340/374 (nm). The mechanism of the interaction between the optical sensor and UO22+ was discussed. The calibration plot was achieved over the concentration range 1.7×10−6-4.9×10−8 mol L−1 with a correlation coefficient of (0.999) and limit of detection (LOD) and limit of quantification (LOQ) are 4.1×10−8 and 1.2×10−7 mol L−1, respectively.