Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5399474 | Journal of Luminescence | 2015 | 27 Pages |
Abstract
Water-soluble CdSe/CdS quantum dots (QDs) modified with thioglycolic acid (TGA) were synthesized. A novel method for determination of sparfloxacin (SPFX) has been developed based on quenching of the fluorescence of QDs at 556 nm wavelength. The optimum fluorescence intensity was found in 0.067 mol Lâ1 KH2PO4-Na2HPO4 buffer solution at pH 6.47 of 3.0Ã10â5 mol Lâ1 QDs. When the concentration of quantum dots is 3.0Ã10â5 mol Lâ1 the fluorescence quenching intensity of QDs is linearly proportional to the concentration of SPFX from 0.5 μg mLâ1 to 30 μg mLâ1, with correlation coefficient R=0.9983. The detection limit for SPFX was 0.1391 μg mLâ1. The method was used for determination of SPFX in tablets, and the results agreed with the claimed value. Trace amounts of SPFX in milk were also determined with the recovery of 95.3-106.8%.
Related Topics
Physical Sciences and Engineering
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Physical and Theoretical Chemistry
Authors
Ming Hou, Xiaoya Yan, Ling Xiong,