| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5399893 | Journal of Luminescence | 2014 | 5 Pages |
Abstract
A metal complex with antitumoral activity, Zn(Curcumin)(bypiridine)Cl, was characterized from a photophysical point of view, showing a green emission and a positive solvatochromism. These characteristics can be conveniently used to study its interaction with Human Serum Albumin (HSA), a protein carrier of many non-aqueous biologically-active compounds in the blood stream. The intrinsic fluorescence of HSA was quenched by Fluorescence Resonance Energy Transfer toward the Zn(II) complex, and the Stern-Volmer equation was applied to determine the bimolecular quenching rate constant of the interaction.
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Authors
Loredana Ricciardi, Daniela Pucci, Sante Pirillo, Massimo La Deda,