Article ID Journal Published Year Pages File Type
5400173 Journal of Luminescence 2014 9 Pages PDF
Abstract
The interaction of HSA/BSA with single and double chain surfactant-cobalt(III) complexes, cis-[Co(phen)2(UA)Cl](ClO4)2·2H2O (1), cis-[Co(phen)2(UA)2](ClO4)3·2H2O (2), cis-[Co(en)2(UA)Cl](ClO4)2·2H2O (3), cis-[Co(en)2(UA)2](ClO4)3·2H2O (4), were investigated by steady state fluorescence, UV-vis absorption, synchronous, three dimensional fluorescence and circular dichroism spectroscopy. The results reveal that the quenching of HSA/BSA by all the four complexes takes place through static mechanism. The binding constant, binding sites and thermodymamic parameter were calculated. The results illustrate that the double chain surfactant-cobalt(III) complexes bind more strongly than the corresponding single chain complexes. The distance between donor (HSA/BSA) and acceptor (surfactant-cobalt(III) complexes) was obtained according to FRET. The results of synchronous, three dimensional and circular dichroism spectroscopy studies show that all the complexes caused considerable amount of conformational and some amount of environment changes in HSA/BSA.
Related Topics
Physical Sciences and Engineering Chemistry Physical and Theoretical Chemistry
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