Article ID Journal Published Year Pages File Type
5401110 Journal of Luminescence 2012 4 Pages PDF
Abstract
► DNA binding studies of the triterpenoid derivative, cholesterol, N,N-Bis(3β-acetoxy-5α-cholest-6-yl-idene)hydrazine. ► The ligand binds to DNA through hydrophobic interaction with Kb value found to be 4.7×103 M−1. ► DNA is probably cleaved by an other than oxidative mechanism, possibly by a discernable hydrolytic pathway. ► In the presence of major and minor groove binding agents, the (L) prefers major groove binding of the DNA.
Related Topics
Physical Sciences and Engineering Chemistry Physical and Theoretical Chemistry
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