Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5401504 | Journal of Luminescence | 2012 | 7 Pages |
Abstract
⺠Our study supply salient clues on the toxicological action of toxic phenosafranine. ⺠Phenosafranine is situated within subdomain IIIA, Sudlow's site II on HSA. ⺠Trp-62, Trp-63 and Trp-108 residues on the Lys molecule are all close to dye. ⺠Static property of the phenosafranine induced quenching of protein Trp fluorescence. ⺠Protein spatial structure proved to be disturbed after complex with phenosafranine.
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Related Topics
Physical Sciences and Engineering
Chemistry
Physical and Theoretical Chemistry
Authors
Fei Ding, Li Zhang, Ye Sun, Jian-Xiong Diao, Xin-Ling Yang, Ying Sun, Li Zhang,