Article ID Journal Published Year Pages File Type
5401626 Journal of Luminescence 2012 6 Pages PDF
Abstract
► We model the binding of β-carboline alkaloids to BSA by using the spectroscopic methods. ► We investigate the effects of drug complexation on BSA stability and conformation. ► A partial protein destabilization occurred at high alkaloids concentration. ► Alkaloids bind BSA via hydrophobic interactions and H-bonding with the NH groups. ► BSA can be considered as a good carrier for transportation of β-carboline alkaloids.
Related Topics
Physical Sciences and Engineering Chemistry Physical and Theoretical Chemistry
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