Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5401626 | Journal of Luminescence | 2012 | 6 Pages |
Abstract
⺠We model the binding of β-carboline alkaloids to BSA by using the spectroscopic methods. ⺠We investigate the effects of drug complexation on BSA stability and conformation. ⺠A partial protein destabilization occurred at high alkaloids concentration. ⺠Alkaloids bind BSA via hydrophobic interactions and H-bonding with the î¸NH groups. ⺠BSA can be considered as a good carrier for transportation of β-carboline alkaloids.
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Authors
Shohreh Nafisi, Ataollah Panahyab, Golshan Bagheri Sadeghi,