| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5401755 | Journal of Luminescence | 2012 | 6 Pages |
Abstract
⺠2-ABT interacts with hs-DNA in minor groove binding mode to form complex in the ratio 1:1. ⺠DNA conformation changes after binding with 2-ABT. ⺠ABT-DNA complex is simulated using Autodock and binding free energy is also calculated. ⺠Besides Van der Waals force, hydrogen bond between adenine and 2-ABT plays an important role. ⺠Sequence specificity of the binding is verified by the effect of DNA bases on 2-ABT.
Related Topics
Physical Sciences and Engineering
Chemistry
Physical and Theoretical Chemistry
Authors
Yajing Sun, Fanying Ji, Rutao Liu, Jing Lin, Qifei Xu, Canzhu Gao,