Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5401824 | Journal of Luminescence | 2012 | 6 Pages |
Abstract
⺠Complex formation is dominant for the reduction of BSA fluorescence. ⺠Primary binding site for drug is located in the sub-domain IIA of BSA. ⺠Electrostatic force played a main role between the drug and the BSA. ⺠The BSA structure changes upon drug complexation. ⺠Higher concentrations of metal ions have good effects to improve efficacy of drug except Cu2+.
Related Topics
Physical Sciences and Engineering
Chemistry
Physical and Theoretical Chemistry
Authors
Baosheng Liu, Chao Yang, Xiaona Yan, Jing Wang, Yunkai Lv,