Article ID Journal Published Year Pages File Type
5401824 Journal of Luminescence 2012 6 Pages PDF
Abstract
► Complex formation is dominant for the reduction of BSA fluorescence. ► Primary binding site for drug is located in the sub-domain IIA of BSA. ► Electrostatic force played a main role between the drug and the BSA. ► The BSA structure changes upon drug complexation. ► Higher concentrations of metal ions have good effects to improve efficacy of drug except Cu2+.
Related Topics
Physical Sciences and Engineering Chemistry Physical and Theoretical Chemistry
Authors
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