Application of quantitative structure-activity relationship to the determination of binding constant based on fluorescence quenching

Article ID	Journal	Published Year	Pages	File Type
5402234	Journal of Luminescence	2011	8 Pages	PDF

Abstract

âº QSAR models for binding constants of some compounds to HSA were developed. âº The models provide a simple and straightforward way to predict binding constant. âº QSAR can give some insight into structural features related to binding behavior.

Keywords

Binding constant Fluorescence quenching Quantitative structure–activity relationship Multiple linear regression Radial basis function neural network

Related Topics

Physical Sciences and Engineering Chemistry Physical and Theoretical Chemistry

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Application of quantitative structure-activity relationship to the determination of binding constant based on fluorescence quenching

Authors

Yingying Wen, Huitao Liu, Feng Luan, Yuan Gao,