Article ID Journal Published Year Pages File Type
5405118 Journal of Magnetic Resonance 2015 26 Pages PDF
Abstract

- The multiplicity-separated (MS) 1H-15N and 1H-13C HSQC experiments are presented.
- The MS-HSQC pulse sequence has better separation and sensitivity than the standard edited HSQC.
- The MS-HSQCs work on biomolecule samples at natural abundance in aqueous solution and can be applied to protein drugs.
Keywords
Related Topics
Physical Sciences and Engineering Chemistry Physical and Theoretical Chemistry
Preview
NMR profiling of biomolecules at natural abundance using 2D 1H-15N and 1H-13C multiplicity-separated (MS) HSQC spectra
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