Sensitivities of statistical distribution model and diffusion kurtosis model in varying microstructural environments: A Monte Carlo study

► The ADC was sensitive to all the microstructural changes except the decrease in P. ► The σstat was specifically sensitive to the increase and decrease in V. ► The Kapp was specifically sensitive to the decrease in 2R and the increase in P. ► The diffusion models have different, specific microstructural sensitivity. ► A combination of the models may give insights into the microstructural changes.