Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5405766 | Journal of Magnetic Resonance | 2013 | 14 Pages |
Abstract
⸠Interaction with HSA of 20 common blood plasma metabolites is investigated by NMR. ⸠Most of these metabolites bind to HSA, but are released by fatty acids. ⸠Competition for HSA binding is absent for most of these metabolites. ⸠Protein removal by ultrafiltration does not remove metabolite, citrate excepted. ⸠These mappings provide leads to improved NMR metabolic profiling of blood plasma.
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Authors
Marc Jupin, Paul J. Michiels, Frederic C. Girard, Manfred Spraul, Sybren S. Wijmenga,