Article ID Journal Published Year Pages File Type
5407860 Journal of Magnetic Resonance 2006 6 Pages PDF
Abstract
We demonstrate the feasibility of recording 1H-15N correlation spectra of proteins in only one second of acquisition time. The experiment combines recently proposed SOFAST-HMQC with Hadamard-type 15N frequency encoding. This allows site-resolved real-time NMR studies of kinetic processes in proteins with an increased time resolution. The sensitivity of the experiment is sufficient to be applicable to a wide range of molecular systems available at millimolar concentration on a high magnetic field spectrometer.
Related Topics
Physical Sciences and Engineering Chemistry Physical and Theoretical Chemistry
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