| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5407880 | Journal of Magnetic Resonance | 2006 | 4 Pages |
Abstract
The problem of the relaxation of identical spins 1/2 induced by chemical exchange between spins with different chemical shifts in the presence of time-dependent RF irradiation (in the first rotating frame) is considered for the fast exchange regime. The solution for the time evolution under the chemical exchange Hamiltonian in the tilted doubly rotating frame (TDRF) is presented. Detailed derivation is specified to the case of a two-site chemical exchange system with complete randomization between jumps of the exchanging spins. The derived theory can be applied to describe the modulation of the chemical exchange relaxation rate constants when using a train of adiabatic pulses, such as the hyperbolic secant pulse. Theory presented is valid for quantification of the exchange-induced time-dependent rotating frame longitudinal T1Ï,ex and transverse T2Ï,ex relaxations in the fast chemical exchange regime.
Related Topics
Physical Sciences and Engineering
Chemistry
Physical and Theoretical Chemistry
Authors
Dennis J. Sorce, Shalom Michaeli, Michael Garwood,