Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5410624 | Journal of Molecular Liquids | 2015 | 5 Pages |
Abstract
Equilibrium solubility of sodium sulfadiazine (Na.SDZ), sodium sulfamerazine (Na.SMR), and sodium sulfamethazine (Na.SMT), was determined in aqueous binary mixtures of propylene glycol (PG) at 298.15 K. If the solubility values expressed in both concentration scales are considered, i.e. mole fraction and molarity, in water-rich mixtures the solubility decrease as: Na.SDZ > Na.SMT > Na.SMR, whereas, in PG-rich mixtures the observed order is: Na.SMT > Na.SDZ > Na.SMR. In all cases the solubility in neat water is higher than those in neat PG. Correlation of the solubility data obtained was made by means of the Jouyban-Acree model for all the sodium sulfonamides. Otherwise, apparent specific volumes (ÏVsp) of sodium sulfonamides at saturation were also calculated in all the mixtures. The average ÏVsp values are as follows: 0.663 cm3 gâ 1 for Na.SDZ, 0.723 cm3 gâ 1 for Na.SMR, and 0.740 cm3 gâ 1 for Na.SMT, with a variation lower than 5.0% in each case.
Related Topics
Physical Sciences and Engineering
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Physical and Theoretical Chemistry
Authors
MarÃa M. Muñoz, Carlos J. RodrÃguez, Daniel R. Delgado, MarÃa Á. Peña, Abolghasem Jouyban, Fleming MartÃnez,