Structural, thermal, kinetic and pharmacology in vitro studies of H-bonded complexes formed between the sedative-hypnotic drug 5,5-diethylbarbituratic acid with various acceptors: Liquid and solid characterization

The complexation of BA with DNB leads to a highly well-defined microstructure in the nano-scale. This magnified SEM micrograph at a high magnification (× 20 000) shows a smooth sheet-like-shaped morphology with a particle size of ~ 5 μm. Such a microstructure offers large surface area.