| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5416270 | Journal of Molecular Structure: THEOCHEM | 2010 | 4 Pages |
Abstract
Nucleophilic epoxide ring opening reactions can be effectively carried out with BF3 but not with BH3. This has been traced to the formation of an intermediate with an intramolecular dihydrogen bond which prefers to yield a species with frustrated Lewis acid-base pair after liberating H2 molecule in the BH3 catalyzed system. Quantum chemical analysis indicates that the H2 liberation is more favorable by 37.8Â kcal/mol in comparison to the desired aminoalcohol formation.
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Authors
Vaibhav A. Dixit, Prakash C. Rathi, Prasad V. Bharatam,