Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5416707 | Journal of Molecular Structure: THEOCHEM | 2010 | 5 Pages |
Abstract
The stability and structure of 5-telluro-2â²-deoxyuridine and 5-telluro-2â²-deoxyuridine-3â²,5â²-biphosphate cations was investigated by density functional theory calculations. With regard to a conceivable Coulomb explosion within the DNA strand after the decay of DNA-incorporated 125I or 123I, the phosphate groups in 5-telluro-2â²-deoxyuridine-3â²,5â²-biphosphate have a strongly stabilizing effect on the DNA component.
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Authors
E.A. Kümmerle, E. Pomplun,