| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5419292 | Journal of Molecular Structure: THEOCHEM | 2006 | 5 Pages |
Abstract
The chair conformation of the forming ring in the transition structure, for its high stability, is usually considered for the determination of the overall stereoselectivity in a type-II ene cyclization reaction. However, present theoretical investigation reveals that the presence of a heteroatom like oxygen or nitrogen in the tether of type-II carbonyl ene cyclization stabilizes the transition structure, in which the forming ring adopts a boat conformation. Due to such stability of the boat conformer the overall stereoselectivity of some type-II reactions may differ from the expected one.
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Authors
Kuheli Chakrabarty, Sukhendu Roy, Gourab Kanti Das,