Article ID Journal Published Year Pages File Type
5419607 Progress in Nuclear Magnetic Resonance Spectroscopy 2012 33 Pages PDF
Abstract

► 19F molecular tags and labeling protocols for 19F NMR studies of proteins are reviewed and contrasted. ► 19F NMR biosynthetic labeling strategies are presented. ► Experimental challenges (loss of function through labeling, line broadening, assignment ambiguities) are discussed. ► Approaches to the study of protein topology, using 19F NMR, are presented. ► Current examples of protein NMR studies are given.

Related Topics
Physical Sciences and Engineering Chemistry Physical and Theoretical Chemistry
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