Ligand- and substrate-based 19F NMR screening: Principles and applications to drug discovery

Article ID	Journal	Published Year	Pages	File Type
5419759	Progress in Nuclear Magnetic Resonance Spectroscopy	2007	29 Pages	PDF

Keywords

STD WaterLOGSY spam filter FBDD PFG FKBP12 SAR ITC FBS HTS HSA CPMG Chemical shift anisotropy Carr–Purcell–Meiboom–Gill human serum albumin CSA Fluorescence anisotropy Saturation transfer difference Structure–activity relationship Alarm Fragment-based drug design high-throughput screening Fragment-based screening Fabs fluorescence polarization ERETIC Enzyme inhibition BEI FK506 binding protein Isothermal titration calorimetry Drug discovery

Related Topics

Physical Sciences and Engineering Chemistry Physical and Theoretical Chemistry

Ligand- and substrate-based 19F NMR screening: Principles and applications to drug discovery

Authors

Claudio Dalvit,