| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5434423 | Materials Science and Engineering: C | 2017 | 5 Pages |
â¢Chlorhexidine acetate (CA) was applied as both antimicrobial drug and surfactant for microcapsule preparation.â¢With CA and silver nanoparticle, composite microcapsules promise a rapid and sustained antibacterial effect.â¢Composite microcapsules can be modified on the surface of polymer film, promising applications on surgical dressing, etc.
In this study, composite antibacterial microcapsules combining of two antibacterial agents: chlorhexidine acetate and silver nanoparticle were prepared. The chlorhexidine acetate was encapsulated inside of the microcapsules and nano-sized silver particles were modified on the surface of microcapsules by electrostatic adsorption methods. Results show that this method decreases the silver usage dramatically, and promises a sustained antibacterial effect >Â 30Â days. These microcapsules can also be modified on the surface of polymer films easily, which demonstrated the potential in functionalizing the implanted materials with antibacterial property.
Graphical abstractDownload high-res image (73KB)Download full-size image
