Article ID Journal Published Year Pages File Type
5434760 Materials Science and Engineering: C 2017 13 Pages PDF
Abstract

•Biodegradable FePd2 (wt%) alloy was prepared by different routes.•Alloying with Pd enhances both strength and corrosion rate compared with pure iron.•Combination of mechanical alloying and spark plasma sintering allows preparation of high strength materials.•Combination of mechanical alloying and space holder technique leads to high degradation rates.•FePd2 (wt%) alloy prepared by different routes showed acceptable cytotoxicity.

Recently, iron-based materials have been considered as candidates for the fabrication of biodegradable load-bearing implants. Alloying with palladium has been found to be a suitable approach to enhance the insufficient corrosion rate of iron-based alloys. In this work, we have extensively compared the microstructure, the mechanical and corrosion properties, and the cytotoxicity of an FePd2 (wt%) alloy prepared by three different routes - casting, mechanical alloying and spark plasma sintering (SPS), and mechanical alloying and the space holder technique (SHT). The properties of the FePd2 (wt%) were compared with pure Fe prepared in the same processes. The preparation route significantly influenced the material properties. Materials prepared by SPS possessed the highest values of mechanical properties (CYS ~ 750-850 MPa) and higher corrosion rates than the casted materials. Materials prepared by SHT contained approximately 60% porosity; therefore, their mechanical properties reached the lowest values, and they had the highest corrosion rates, approximately 0.7-1.2 mm/a. Highly porous FePd2 was tested in vitro according to the ISO 10993-5 standard using L929 cells, and two-fold diluted extracts showed acceptable cytocompatibility. In general, alloying with Pd enhanced both mechanical properties and corrosion rates and did not decrease the cytocompatibility of the studied materials.

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