Article ID Journal Published Year Pages File Type
5434998 Materials Science and Engineering: C 2017 6 Pages PDF
Abstract

•Personalized medicine is emerging as a promising and appealing therapeutic option.•Platelet rich plasma mimics and enhances the body's innate healing process.•Cells, growth factors and scaffolds are essential for tissue regeneration.•Autologous therapies provide natural scaffolds and a sustained release of proteins.

As social and health needs are changing, new challenges to develop innovative alternatives arise to address unmet medical needs. Personalized medicine is emerging as a promising and appealing therapeutic option. The use of patient's own plasma and platelets as therapeutics is providing new avenues in the treatment of acute and chronic tissue injuries by promoting tissue repair and regeneration. Plasma and platelet-based therapies mimic the physiological repair process by releasing autologous growth factors and creating a natural, biodegradable and transient scaffold that acts as transient matrix. This review summarizes the recent advances and challenges in the field of personalized plasma-based medicine and its potential to treat age-related diseases.

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Physical Sciences and Engineering Materials Science Biomaterials
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