| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5462809 | Materials Letters | 2017 | 10 Pages |
Abstract
A novel form of carbon dots (PEG-CDs) was prepared by using one-step hydrothermal synthesis with glycine as the precursor and polyethylene glycol (PEG)-2000 as the surface modifier. The prepared PEG-CDs were characterized with HRTEM, XRD, PL, FTIR and UV. The results showed that they were quasi spherical particles with a diameter of approximately 12Â nm and had a fine fluorescence property, good water solubility, favorable stability and high quantum yield with 28.58%. Doxorubicin hydrochloride (DOX) as a potential anti-cancer drug was loaded on the PEG-CDs. The drug loading capacity was 24.25Â mg/g and the encapsulation efficiency was 77.23% at pH 9.0 with 36Â h of dialysis; DOX release in PBS system with a pH of 5.5 could reach up to 76.67% in 23Â h.
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Authors
Xin Zhang, Yongbo Wang, Wenwei Liu, Xuhua Liang, Boni Si, Enzhou Liu, Xiaoyun Hu, Jun Fan,