| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5463422 | Materials Letters | 2017 | 9 Pages |
Abstract
Polydopamine (PDA)/casein phosphopeptide (CPP) bilayers were prepared on titanium (Ti) substrates through a simple two-step immersion process at room temperature. The adhering PDA interlayers linked the natural biomolecule, CPP, to the Ti surface via covalent bonds. The outer layer of CPP served as a template to bind Ca2+ and thus promoted nucleation and growth of hydroxyapatite (HA). Our results indicate that: (i) PDA and CPP can be successfully grafted onto Ti substrates; (ii) an HA coating can be formed within 1Â day through the biomimetic HA coating method on the Ti substrate modified with PDA/CPP bilayer; and (iii) no cracking is observed in the HA coating, indicating stable binding between HA and the modified substrate.
Keywords
Related Topics
Physical Sciences and Engineering
Materials Science
Nanotechnology
Authors
Meng Wu, Tao Wang, Jiamin Zhang, Haimei Qian, Runjie Miao, Xin Yang,