Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5463865 | Materials Letters | 2017 | 6 Pages |
Abstract
In this study, a new absorbable hemostat was developed with two most abundantly found natural polymers. Oxidized nanofibrillar cellulose (ONFC)-chitosan (Ch) sponge was prepared by lyophilization at a volume ratio of 50:50. Cytotoxicity and cell proliferation studies revealed that the sponge was non-cytotoxic and the cell proliferated continuously on the sponge. ONFC-Ch sponge showed better hemostatic effect on hepatic trauma than ONFC sponge. Both sponges were implanted on hepatic trauma for 1 and 3Â weeks. ONFC-Ch sponge showed greater degree biodegradability and biocompatibility. Thus, ONFC-Ch sponge can be considered as a potential hemostatic material.
Keywords
Related Topics
Physical Sciences and Engineering
Materials Science
Nanotechnology
Authors
Mousumi Sukul, Reiza D. Ventura, Sang Ho Bae, Hwan Jun Choi, Sun Young Lee, Byong Taek Lee,