Article ID Journal Published Year Pages File Type
5464262 Materials Letters 2017 9 Pages PDF
Abstract
Both protein capsules and gold nanoparticles have attracted considerable attention in drug delivery systems. In this study, silk fibroin nanocapsules were fabricated by silk-on-silk layer-by-layer (LbL) assembly onto poly[lactic-co-(glycolic acid)] (PLGA) sacrificial templates followed by core removal. Subsequently, hybrid nanocapsules were fabricated by physical adsorption of DNA modified gold nanospheres and nanorods. These hybrid LbL-nanocapsules have potential applications for targeted drug delivery or combination therapy.
Related Topics
Physical Sciences and Engineering Materials Science Nanotechnology
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