Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5464262 | Materials Letters | 2017 | 9 Pages |
Abstract
Both protein capsules and gold nanoparticles have attracted considerable attention in drug delivery systems. In this study, silk fibroin nanocapsules were fabricated by silk-on-silk layer-by-layer (LbL) assembly onto poly[lactic-co-(glycolic acid)] (PLGA) sacrificial templates followed by core removal. Subsequently, hybrid nanocapsules were fabricated by physical adsorption of DNA modified gold nanospheres and nanorods. These hybrid LbL-nanocapsules have potential applications for targeted drug delivery or combination therapy.
Related Topics
Physical Sciences and Engineering
Materials Science
Nanotechnology
Authors
Bo Du, Hongwei Wang, Hongbo Tang, Man Guan, Jingjie Wang, Zhe Zhang, Zhimin Zhou, Qiqing Zhang,