Refrigerant R32 as lower GWP working fluid in residential air conditioning systems in Europe and the USA

To replace R410A under extreme conditions, some system modifications can be conducted, or R32 mixtures with hydrofluoroolefins (HFOs) can be used. Such mixtures achieve a lower performance than R32, but are acceptable replacements when considering their lower GWP compared to that of R32, and similar level of flammability. Finally, other (R32-based) alternative mixtures have also been developed and their behaviours studied under a wide range of operating conditions.