Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5497128 | Physics Procedia | 2016 | 7 Pages |
Abstract
Modern-day histology of bio-tissues for supporting stratified medicine diagnoses requires high-precision cutting to ensure high quality extremely thin specimens used in analysis. Additionally, the cutting quality is significantly affected by a wide variety of soft and hard tissues in the samples. This paper deals with development of a next generation of microtome employing introduction of controlled ultrasonic vibration to realise a hybrid cutting process of bio-tissues. The study is based on a combination of advanced experimental and numerical (finite-element) studies of multi-body dynamics of a cutting system. The quality of cut samples produced with the prototype is compared with the state-of-the-art.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Physics and Astronomy (General)
Authors
Dong Wang, Anish Roy, Vadim V. Silberschmidt,