| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5500607 | Ageing Research Reviews | 2017 | 41 Pages |
Abstract
Currently, the availability of platforms that discriminates between the presence of 5mC and 5hmC at single-base resolution is starting to shed light on the functions of 5hmC. In this review, we provide an overview of the genomic distribution of 5hmC, and examine recent findings on the role of this mark and the potential consequences of its misregulation during three fundamental biological processes: cell differentiation, cancer and aging.
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Ageing
Authors
V. López, A.F. Fernández, M.F. Fraga,