Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5500927 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2017 | 27 Pages |
Abstract
Inactivation of GSK-3β up-regulates skeletal muscle mitochondrial metabolism and increases expression levels of PGC-1 signaling constituents. In vivo, GSK-3β KO protects against inactivity-induced reductions in muscle metabolic gene expression.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Ageing
Authors
W.F. Theeuwes, H.R. Gosker, R.C.J. Langen, K.J.P. Verhees, N.A.M. Pansters, A.M.W.J. Schols, A.H.V. Remels,