| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5500949 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2017 | 39 Pages |
Abstract
Increased retinal PARP-1 in diabetes increases its complex formation with the transcription factors at the MMP-9 promoter, subsequently increasing MMP-9 expression. Inhibition of PARP-1, inhibits, diabetes-induced increase in MMP-9, mitochondrial damage and capillary cell apoptosis.68
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Authors
Manish Mishra, Renu A. Kowluru,